6H04

Closed conformation of the Membrane Attack Complex

Summary for 6H04

• Entry DOI: 10.2210/pdb6h04/pdb
• Related: 6H03
• EMDB information: 0106 0107 0109 0110 0111 0112 0113
• Descriptor: Complement component C9, Complement C5,Complement C5, Complement component C8 beta chain, ... (9 entities in total)
• Functional Keywords: c5b9, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 24
• Total formula weight: 1630274.35

Authors

Menny, A.,Serna, M.,Boyd, C.M.,Gardner, S.,Joseph, A.P.,Topf, M.,Bubeck, D. (deposition date: 2018-07-06, release date: 2018-12-19, Last modification date: 2020-07-29)

• Primary citation: Menny, A.,Serna, M.,Boyd, C.M.,Gardner, S.,Joseph, A.P.,Morgan, B.P.,Topf, M.,Brooks, N.J.,Bubeck, D.; CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.; Nat Commun, 9:5316-5316, 2018; PubMed: 30552328; DOI: 10.1038/s41467-018-07653-5

Experimental method

ELECTRON MICROSCOPY (5.6 Å)