6F1C
C1rC1s complex
Summary for 6F1C
Entry DOI | 10.2210/pdb6f1c/pdb |
Descriptor | Complement C1r subcomponent, Complement C1s subcomponent, beta-D-galactopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | cub domain, egf-like domain, complement, c1r-c1s, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 132949.33 |
Authors | Almitairi, J.O.M.,Venkatraman Girija, U.,Furze, C.M.,Simpson-Gray, X.,Badakshi, F.,Marshall, J.E.,Mitchell, D.A.,Moody, P.C.E.,Wallis, R. (deposition date: 2017-11-21, release date: 2018-01-17, Last modification date: 2024-01-17) |
Primary citation | Almitairi, J.O.M.,Venkatraman Girija, U.,Furze, C.M.,Simpson-Gray, X.,Badakshi, F.,Marshall, J.E.,Schwaeble, W.J.,Mitchell, D.A.,Moody, P.C.E.,Wallis, R. Structure of the C1r-C1s interaction of the C1 complex of complement activation. Proc. Natl. Acad. Sci. U.S.A., 115:768-773, 2018 Cited by PubMed: 29311313DOI: 10.1073/pnas.1718709115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.2 Å) |
Structure validation
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