6DFX
human diabetogenic TCR T1D3 in complex with DQ8-p8E9E peptide
Summary for 6DFX
Entry DOI | 10.2210/pdb6dfx/pdb |
Related | 6DFS |
Descriptor | MHC class II HLA-DQ-alpha chain, MHC class II antigen, T1D3 alpha chain, ... (8 entities in total) |
Functional Keywords | t cell receptor, type 1 diabetes, autoimmunity, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 193195.87 |
Authors | |
Primary citation | Wang, Y.,Sosinowski, T.,Novikov, A.,Crawford, F.,White, J.,Jin, N.,Liu, Z.,Zou, J.,Neau, D.,Davidson, H.W.,Nakayama, M.,Kwok, W.W.,Gapin, L.,Marrack, P.,Kappler, J.W.,Dai, S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol, 4:-, 2019 Cited by PubMed: 30952805DOI: 10.1126/sciimmunol.aav7517 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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