6DC6

Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin

Summary for 6DC6

• Entry DOI: 10.2210/pdb6dc6/pdb
• Descriptor: Ubiquitin-like modifier-activating enzyme 1, Ubiquitin, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: ubiquitin, e1, adenylation, thioester bond, e2, transthiolation, signaling protein, signaling protein-ligase complex, signaling protein/ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 245272.96

Authors

Lv, Z.,Yuan, L.,Williams, K.M.,Atkison, J.H.,Olsen, S.K. (deposition date: 2018-05-04, release date: 2018-10-10, Last modification date: 2023-10-11)

• Primary citation: Lv, Z.,Williams, K.M.,Yuan, L.,Atkison, J.H.,Olsen, S.K.; Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity.; J. Biol. Chem., 293:18337-18352, 2018; PubMed: 30279270; DOI: 10.1074/jbc.RA118.003975

Experimental method

X-RAY DIFFRACTION (3.14 Å)