5ZTM
Crystal structure of MLE dsRBDs in complex with roX2 (R2H1)
Summary for 5ZTM
Entry DOI | 10.2210/pdb5ztm/pdb |
Descriptor | Dosage compensation regulator, non-coding mRNA sequence roX2 (2 entities in total) |
Functional Keywords | helicase, lncrna, hydrolase-rna complex, hydrolase/rna |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 76354.92 |
Authors | Lv, M.Q.,Tang, Y.J. (deposition date: 2018-05-04, release date: 2019-03-06, Last modification date: 2023-11-22) |
Primary citation | Lv, M.,Yao, Y.,Li, F.,Xu, L.,Yang, L.,Gong, Q.,Xu, Y.Z.,Shi, Y.,Fan, Y.J.,Tang, Y. Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila. Nucleic Acids Res., 47:3142-3157, 2019 Cited by PubMed: 30649456DOI: 10.1093/nar/gky1308 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.899 Å) |
Structure validation
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