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5ZTM

Crystal structure of MLE dsRBDs in complex with roX2 (R2H1)

Summary for 5ZTM
Entry DOI10.2210/pdb5ztm/pdb
DescriptorDosage compensation regulator, non-coding mRNA sequence roX2 (2 entities in total)
Functional Keywordshelicase, lncrna, hydrolase-rna complex, hydrolase/rna
Biological sourceDrosophila melanogaster (Fruit fly)
More
Total number of polymer chains3
Total formula weight76354.92
Authors
Lv, M.Q.,Tang, Y.J. (deposition date: 2018-05-04, release date: 2019-03-06, Last modification date: 2023-11-22)
Primary citationLv, M.,Yao, Y.,Li, F.,Xu, L.,Yang, L.,Gong, Q.,Xu, Y.Z.,Shi, Y.,Fan, Y.J.,Tang, Y.
Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila.
Nucleic Acids Res., 47:3142-3157, 2019
Cited by
PubMed: 30649456
DOI: 10.1093/nar/gky1308
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.899 Å)
Structure validation

217705

數據於2024-03-27公開中

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