5ZRX

Crystal Structure of EphA2/SHIP2 Complex

Summary for 5ZRX

• Entry DOI: 10.2210/pdb5zrx/pdb
• Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2 (2 entities in total)
• Functional Keywords: sam domain, heterodimer, signaling protein, cell signaling, receptor, transmembrane, tyrosine-protein kinase, cell adhesion, protein binding
• Biological source: Mus musculus (Mouse); More
• Cellular location: Cell membrane ; Single-pass type I membrane protein : Q03145
• Total number of polymer chains: 2
• Total formula weight: 35243.34

Authors

Wang, Y.,Shang, Y.,Li, J.,Chen, W.,Li, G.,Wan, J.,Liu, W.,Zhang, M. (deposition date: 2018-04-25, release date: 2018-05-30, Last modification date: 2023-11-22)

• Primary citation: Wang, Y.,Shang, Y.,Li, J.,Chen, W.,Li, G.,Wan, J.,Liu, W.,Zhang, M.; Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.; Elife, 7:-, 2018; PubMed: 29749928; DOI: 10.7554/eLife.35677

Experimental method

X-RAY DIFFRACTION (1.5 Å)