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5ZMQ

Crystal structure of Zika NS3 protease with phenylacetyl-Lys-Lys-Arg-COOH inhibitor

Summary for 5ZMQ
Entry DOI10.2210/pdb5zmq/pdb
Related PRD IDPRD_002309
DescriptorSerine protease subunit NS2B, Serine protease NS3, peptide PAC-DLY-DLY-DAR, ... (4 entities in total)
Functional Keywordsviral protease, serine protease, non-structural protein 3, zika protease, viral protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceZika virus (ZIKV)
More
Total number of polymer chains10
Total formula weight100647.02
Authors
Phoo, W.W.,Wirawan, M. (deposition date: 2018-04-05, release date: 2018-10-17, Last modification date: 2023-11-22)
Primary citationPhoo, W.W.,Zhang, Z.,Wirawan, M.,Chew, E.J.C.,Chew, A.B.L.,Kouretova, J.,Steinmetzer, T.,Luo, D.
Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.
Antiviral Res., 160:17-24, 2018
Cited by
PubMed: 30315877
DOI: 10.1016/j.antiviral.2018.10.006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.987 Å)
Structure validation

217705

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