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5ZKP

Crystal structure of the human platelet-activating factor receptor in complex with SR 27417

Summary for 5ZKP
Entry DOI10.2210/pdb5zkp/pdb
DescriptorPlatelet-activating factor receptor,Flavodoxin,Platelet-activating factor receptor, N1,N1-dimethyl-N2-[(pyridin-3-yl)methyl]-N2-{4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl}ethane-1,2-diamine, FLAVIN MONONUCLEOTIDE (3 entities in total)
Functional Keywordsg protein-coupled receptor, platelet-activating factor receptor, complex, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains1
Total formula weight53351.53
Authors
Cao, C.,Zhao, Q.,Zhang, X.C.,Wu, B. (deposition date: 2018-03-25, release date: 2018-06-20, Last modification date: 2023-11-22)
Primary citationCao, C.,Tan, Q.,Xu, C.,He, L.,Yang, L.,Zhou, Y.,Zhou, Y.,Qiao, A.,Lu, M.,Yi, C.,Han, G.W.,Wang, X.,Li, X.,Yang, H.,Rao, Z.,Jiang, H.,Zhao, Y.,Liu, J.,Stevens, R.C.,Zhao, Q.,Zhang, X.C.,Wu, B.
Structural basis for signal recognition and transduction by platelet-activating-factor receptor.
Nat. Struct. Mol. Biol., 25:488-495, 2018
Cited by
PubMed: 29808000
DOI: 10.1038/s41594-018-0068-y
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.81 Å)
Structure validation

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