5ZIT

Crystal structure of human Entervirus D68 RdRp in complex with NADPH

Summary for 5ZIT

DescriptorRdRp, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywordsevd68-rdrp, complex, inhibitor, nadph-na4, structure-based design, rna binding protein
Biological sourceEnterovirus D68
Total number of polymer chains1
Total molecular weight53510.22
Authors
Wang, M.L.,Zhang, Y.,Dou, Y.S.,Chen, Y.P.,Lu, D.R.,Jiang, H.,Chen, Y.J.,Li, L.,Zhang, C.H.,Shi, Q.L.,Su, D. (deposition date: 2018-03-17, release date: 2019-04-17)
Primary citation
Wang, M.L.,Zhang, Y.,Dou, Y.S.,Chen, Y.P.,Lu, D.R.,Jiang, H.,Chen, Y.J.,Li, L.,Zhang, C.H.,Shi, Q.L.,Su, D.
Crystal structure of human Entervirus D68 RdRp in complex with NADPH
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.196 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25526 1.5% 9.1% 0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5zit
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Molmil generated image of 5zit
rotated about x axis by 90°
Molmil generated image of 5zit
rotated about y axis by 90°