5ZBZ

Crystal structure of the DEAD domain of Human eIF4A with sanguinarine

Summary for 5ZBZ

DescriptorEukaryotic initiation factor 4A-I, 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, MALONATE ION, ... (4 entities in total)
Functional Keywordseukaryotic translation initiation factor 4a, sanguinarine, inhibitor, translation, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight25360.47
Authors
Ding, Y.,Ding, L. (deposition date: 2018-02-14, release date: 2019-02-20)
Primary citation
Ding, Y.,Ding, L.
Crystal structure of the DEAD domain of Human eIF4A with sanguinarine
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.30860259206 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.210500 6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5zbz
no rotation
Molmil generated image of 5zbz
rotated about x axis by 90°
Molmil generated image of 5zbz
rotated about y axis by 90°