5Z57

Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom

This is a non-PDB format compatible entry.

Summary for 5Z57

• Entry DOI: 10.2210/pdb5z57/pdb
• Related: 5Z56 5Z58
• EMDB information: 6889 6890 6891
• Descriptor: Pre-mRNA-processing-splicing factor 8, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, ... (52 entities in total)
• Functional Keywords: spliceosome; cryo-em structure; activated spliceosome; late bact complex; pre-mrna splicing, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 57
• Total formula weight: 3510093.83

Authors

Zhang, X.,Yan, C.,Zhan, X.,Li, L.,Lei, J.,Shi, Y. (deposition date: 2018-01-17, release date: 2018-09-19, Last modification date: 2020-10-14)

• Primary citation: Zhang, X.,Yan, C.,Zhan, X.,Li, L.,Lei, J.,Shi, Y.; Structure of the human activated spliceosome in three conformational states.; Cell Res., 28:307-322, 2018; PubMed: 29360106; DOI: 10.1038/cr.2018.14

Experimental method

ELECTRON MICROSCOPY (6.5 Å)