5Z2X

Structure of Alcohol dehydrogenase from Kluyveromyces polyspora(KpADH)

Summary for 5Z2X

• Entry DOI: 10.2210/pdb5z2x/pdb
• Descriptor: Alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: alcohol dehydrogenase(kpadh), nadph, oxidoreductase
• Biological source: Vanderwaltozyma polyspora DSM 70294 (Kluyveromyces polysporus)
• Total number of polymer chains: 2
• Total formula weight: 80167.96

Authors

Wang, Y.,Zhou, J.Y.,Hou, X.D.,Xu, G.C.,Wu, L.,Rao, Y.J.,ZHou, J.H.,Ni, Y. (deposition date: 2018-01-04, release date: 2019-01-02, Last modification date: 2023-11-22)

• Primary citation: Zhou, J.Y.,Wang, Y.,Xu, G.C.,Wu, L.,Han, R.Z.,Schwaneberg, U.,Rao, Y.J.,Zhao, Y.L.,Zhou, J.H.,Ni, Y.; Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones.; J. Am. Chem. Soc., 140:12645-12654, 2018; PubMed: 30247889; DOI: 10.1021/jacs.8b08640

Experimental method

X-RAY DIFFRACTION (1.98 Å)