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5Z1R

Crystal Structure Analysis of the BRD4

Summary for 5Z1R
Entry DOI10.2210/pdb5z1r/pdb
DescriptorBromodomain-containing protein 4, 5-bromo-N-(2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywordsbrd4(1), bromodomain, transcription
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight17548.93
Authors
Xu, Y.,Zhang, Y.,Xiang, Q.,Song, M.,Wang, C. (deposition date: 2017-12-28, release date: 2019-01-02, Last modification date: 2024-03-27)
Primary citationXiang, Q.,Zhang, Y.,Li, J.,Xue, X.,Wang, C.,Song, M.,Zhang, C.,Wang, R.,Li, C.,Wu, C.,Zhou, Y.,Yang, X.,Li, G.,Ding, K.,Xu, Y.
Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer.
Acs Med.Chem.Lett., 9:262-267, 2018
Cited by
PubMed: 29541371
DOI: 10.1021/acsmedchemlett.8b00003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.62 Å)
Structure validation

217705

數據於2024-03-27公開中

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