5YUP

Crystal Structure of the Fab fragment of FVIIa antibody mAb4F5

Summary for 5YUP

Entry DOI	10.2210/pdb5yup/pdb
Descriptor	the heavy chain of the Fab fragment of FVIIa antibody mAb4F5, the light chain of the Fab fragment of FVIIa antibody mAb4F5 (3 entities in total)
Functional Keywords	fviia, antibodies, fab4f5, inhibition, coagulation, structural protein, immune system
Biological source	Mus musculus (mouse) More
Total number of polymer chains	2
Total formula weight	47423.72
Authors	Jiang, L.G.,Persson, E.,Huang, M.D. (deposition date: 2017-11-22, release date: 2019-06-19, Last modification date: 2023-11-22)
Primary citation	Jiang, L.G.,Xie, X.,Li, J.,Persson, E.,Huang, M.D. Crystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism. Res Pract Thromb Haemost, 3:412-419, 2019 Cited by PubMed: 31294329 DOI: 10.1002/rth2.12211 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation