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5YUF

Crystal Structure of PML RING tetramer

Summary for 5YUF
Entry DOI10.2210/pdb5yuf/pdb
DescriptorProtein PML, ZINC ION (3 entities in total)
Functional Keywordspml nuclear body biogenesis, sumoylation, ring tetramerization, pml-rara, targeted therapy, oncoprotein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus: P29590
Total number of polymer chains4
Total formula weight22985.64
Authors
Primary citationWang, P.,Benhenda, S.,Wu, H.,Lallemand-Breitenbach, V.,Zhen, T.,Jollivet, F.,Peres, L.,Li, Y.,Chen, S.J.,Chen, Z.,de The, H.,Meng, G.
RING tetramerization is required for nuclear body biogenesis and PML sumoylation.
Nat Commun, 9:1277-1277, 2018
Cited by
PubMed: 29599493
DOI: 10.1038/s41467-018-03498-0
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

217705

數據於2024-03-27公開中

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