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5YNB

Crystal structure of MERS-CoV nsp16/nsp10 complex bound to Sinefungin

Summary for 5YNB
Entry DOI10.2210/pdb5ynb/pdb
Descriptornsp16 protein, nsp10 protein, SINEFUNGIN, ... (5 entities in total)
Functional Keywordsinhibitor, complex, transferase
Biological sourceHuman betacoronavirus 2c EMC/2012
More
Total number of polymer chains2
Total formula weight49152.70
Authors
Wei, S.M.,Yang, L.,Ke, Z.H.,Chen, Y.,Guo, D.Y.,Fan, C.P. (deposition date: 2017-10-24, release date: 2018-12-05, Last modification date: 2023-11-22)
Primary citationWei, S.M.,Yang, L.,Ke, Z.H.,Liu, Q.Y.,Chen, Y.,Yang, Z.Z.,Guo, D.Y.,Fan, C.P.
Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.98 Å)
Structure validation

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