5XSG

Ultrahigh resolution structure of FUS (37-42) SYSGYS determined by MicroED

Summary for 5XSG

Entry DOI	10.2210/pdb5xsg/pdb
Descriptor	RNA-binding protein FUS (2 entities in total)
Functional Keywords	cross-coil amyloid fibril, fus low complexity domain, reversible amyloid fibril, rna granule assembly, rna binding protein
Biological source	Homo sapiens (Human)
Cellular location	Nucleus : P35637
Total number of polymer chains	1
Total formula weight	662.65
Authors	Luo, F.,Gui, X.,Zhou, H.,Li, D.,Li, X.,Liu, C. (deposition date: 2017-06-14, release date: 2018-04-04, Last modification date: 2024-03-27)
Primary citation	Luo, F.,Gui, X.,Zhou, H.,Gu, J.,Li, Y.,Liu, X.,Zhao, M.,Li, D.,Li, X.,Liu, C. Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation. Nat. Struct. Mol. Biol., 25:341-346, 2018 Cited by PubMed: 29610493 DOI: 10.1038/s41594-018-0050-8 PDB entries with the same primary citation
Experimental method	ELECTRON CRYSTALLOGRAPHY (0.73 Å)

Structure validation