5XK9

Crystal structure of Isosesquilavandulyl Diphosphate Synthase from Streptomyces sp. strain CNH-189 in complex with GSPP and DMAPP

Summary for 5XK9

• Entry DOI: 10.2210/pdb5xk9/pdb
• Related: 5XK3 5XK6 5XK7 5XK8
• Descriptor: Undecaprenyl diphosphate synthase, MAGNESIUM ION, GERANYL S-THIOLODIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: prenyltransferase, antibiotic biosynthesis, transferase
• Biological source: Streptomyces sp. CNH189
• Total number of polymer chains: 8
• Total formula weight: 218471.10

Authors

Ko, T.P.,Guo, R.T.,Liu, W.,Chen, C.C.,Gao, J. (deposition date: 2017-05-05, release date: 2018-01-10, Last modification date: 2023-11-22)

• Primary citation: Gao, J.,Ko, T.P.,Chen, L.,Malwal, S.R.,Zhang, J.,Hu, X.,Qu, F.,Liu, W.,Huang, J.W.,Cheng, Y.S.,Chen, C.C.,Yang, Y.,Zhang, Y.,Oldfield, E.,Guo, R.T.; "Head-to-Middle" and "Head-to-Tail" cis-Prenyl Transferases: Structure of Isosesquilavandulyl Diphosphate Synthase.; Angew. Chem. Int. Ed. Engl., 57:683-687, 2018; PubMed: 29215779; DOI: 10.1002/anie.201710185

Experimental method

X-RAY DIFFRACTION (2.137 Å)