5XF1

Structure of the Full-length glucagon class B G protein-coupled receptor

Summary for 5XF1

• Entry DOI: 10.2210/pdb5xf1/pdb
• Related: 5XEZ
• Related PRD ID: PRD_900017
• Descriptor: Glucagon receptor,Endolysin,Glucagon receptor, Antibody mAb1 Heavy chain, Antibody mAb1 Light chain, ... (8 entities in total)
• Functional Keywords: human gcgr receptor, class b, 7tm domain, membrane, lcp, xfel, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 232169.82

Authors

Zhang, H.,Qiao, A.,Yang, D.,Yang, L.,Dai, A.,de Graaf, C.,Reedtz-Runge, S.,Dharmarajan, V.,Zhang, H.,Han, G.W.,Grant, T.,Sierra, R.,Weierstall, U.,Nelson, G.,Liu, W.,Wu, Y.,Ma, L.,Cai, X.,Lin, G.,Wu, X.,Geng, Z.,Dong, Y.,Song, G.,Griffin, P.,Lau, J.,Cherezov, V.,Yang, H.,Hanson, M.,Stevens, R.,Jiang, H.,Wang, M.,Zhao, Q.,Wu, B. (deposition date: 2017-04-06, release date: 2017-05-24, Last modification date: 2023-11-22)

• Primary citation: Zhang, H.,Qiao, A.,Yang, D.,Yang, L.,Dai, A.,de Graaf, C.,Reedtz-Runge, S.,Dharmarajan, V.,Zhang, H.,Han, G.W.,Grant, T.D.,Sierra, R.G.,Weierstall, U.,Nelson, G.,Liu, W.,Wu, Y.,Ma, L.,Cai, X.,Lin, G.,Wu, X.,Geng, Z.,Dong, Y.,Song, G.,Griffin, P.R.,Lau, J.,Cherezov, V.,Yang, H.,Hanson, M.A.,Stevens, R.C.,Zhao, Q.,Jiang, H.,Wang, M.W.,Wu, B.; Structure of the full-length glucagon class B G-protein-coupled receptor.; Nature, 546:259-264, 2017; PubMed: 28514451; DOI: 10.1038/nature22363

Experimental method

X-RAY DIFFRACTION (3.19 Å)