5XF1

Structure of the Full-length glucagon class B G protein-coupled receptor

Summary for 5XF1

Related5XEZ
DescriptorGlucagon receptor,Endolysin,Glucagon receptor, Antibody mAb1 Heavy chain, Antibody mAb1 Light chain, ... (6 entities in total)
Functional Keywordshuman gcgr receptor, class b, 7tm domain, membrane, lcp, xfel, signaling protein
Biological sourceHomo sapiens (Human)
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Cellular locationCell membrane ; Multi-pass membrane protein  P47871
Total number of polymer chains6
Total molecular weight232295.93
Authors
Primary citation
Zhang, H.,Qiao, A.,Yang, D.,Yang, L.,Dai, A.,de Graaf, C.,Reedtz-Runge, S.,Dharmarajan, V.,Zhang, H.,Han, G.W.,Grant, T.D.,Sierra, R.G.,Weierstall, U.,Nelson, G.,Liu, W.,Wu, Y.,Ma, L.,Cai, X.,Lin, G.,Wu, X.,Geng, Z.,Dong, Y.,Song, G.,Griffin, P.R.,Lau, J.,Cherezov, V.,Yang, H.,Hanson, M.A.,Stevens, R.C.,Zhao, Q.,Jiang, H.,Wang, M.W.,Wu, B.
Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546:259-264, 2017
PubMed: 28514451 (PDB entries with the same primary citation)
DOI: 10.1038/nature22363
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.19 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.180207.4%6.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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Molmil generated image of 5xf1
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Molmil generated image of 5xf1
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More Biological unit images

Molmil generated image of 5xf1
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Molmil generated image of 5xf1
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Molmil generated image of 5xf1
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5xf1.pdb1.gz [317.1 KB])
Coordinate files for Biological unit (5xf1.pdb2.gz [300.62 KB])