5WWU

Crystal Structure of HLA-A*2402 in complex with 2009 pandemic influenza A(H1N1) virus and avian influenza A(H5N1) virus-derived peptide H1-25

Summary for 5WWU

• Entry DOI: 10.2210/pdb5wwu/pdb
• Related: 5WWI 5WWJ
• Descriptor: HLA class I histocompatibility antigen, A-24 alpha chain, Beta-2-microglobulin, LEU-TYR-LYS-LYS-LEU-LYS-ARG-GLU-ILE-THR-PHE (3 entities in total)
• Functional Keywords: hla-a*2402, h1n1, h5n1, h1-25, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 44742.84

Authors

Zhao, M.,Liu, K.,Chai, Y.,Qi, J.,Liu, J.,Gao, G.F. (deposition date: 2017-01-05, release date: 2018-01-17, Last modification date: 2019-07-31)

• Primary citation: Zhao, M.,Liu, K.,Luo, J.,Tan, S.,Quan, C.,Zhang, S.,Chai, Y.,Qi, J.,Li, Y.,Bi, Y.,Xiao, H.,Wong, G.,Zhou, J.,Jiang, T.,Liu, W.,Yu, H.,Yan, J.,Liu, Y.,Shu, Y.,Wu, G.,Wu, A.,Gao, G.F.,Liu, W.J.; Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.; Mbio, 9:-, 2018; PubMed: 30087171; DOI: 10.1128/mBio.01408-18

Experimental method

X-RAY DIFFRACTION (2.794 Å)