5WTG

Crystal structure of the Fab fragment of anti-HAV antibody R10

Summary for 5WTG

• Entry DOI: 10.2210/pdb5wtg/pdb
• Descriptor: FAB Light chain, FAB Heavy chain (2 entities in total)
• Functional Keywords: hav, neutralizing mechanism, receptor recognition, viral entry, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 4
• Total formula weight: 93916.38

Authors

Wang, X.,Zhu, L.,Dang, M.,Hu, Z.,Gao, Q.,Yuan, S.,Sun, Y.,Zhang, B.,Ren, J.,Walter, T.S.,Wang, J.,Fry, E.E.,Stuart, D.I.,Rao, Z. (deposition date: 2016-12-11, release date: 2017-01-25, Last modification date: 2023-11-08)

• Primary citation: Wang, X.,Zhu, L.,Dang, M.,Hu, Z.,Gao, Q.,Yuan, S.,Sun, Y.,Zhang, B.,Ren, J.,Kotecha, A.,Walter, T.S.,Wang, J.,Fry, E.E.,Stuart, D.I.,Rao, Z.; Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site; Proc. Natl. Acad. Sci. U.S.A., 114:770-775, 2017; PubMed: 28074040; DOI: 10.1073/pnas.1616502114

Experimental method

X-RAY DIFFRACTION (2.907 Å)