5W1Y

SETD8 in complex with a covalent inhibitor

5W1Y の概要

• エントリーDOI: 10.2210/pdb5w1y/pdb
• 分子名称: N-lysine methyltransferase KMT5A, 2-(4-methylpiperazin-1-yl)-3-(phenylsulfanyl)naphthalene-1,4-dione, UNKNOWN ATOM OR ION, ... (4 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus: Q9NQR1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38277.30

構造登録者

Tempel, W.,Yu, W.,Li, Y.,Blum, G.,Luo, M.,Pittella-Silva, F.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Structural Genomics Consortium (SGC) (登録日: 2017-06-05, 公開日: 2017-06-21, 最終更新日: 2023-10-04)

• 主引用文献: Tempel, W.,Yu, W.,Li, Y.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Structural Genomics Consortium (SGC); SETD8 in complex with a covalent inhibitor; to be published,

実験手法

X-RAY DIFFRACTION (1.7 Å)