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5VKG

Solution-state NMR structural ensemble of human Tsg101 UEV in complex with tenatoprazole

Summary for 5VKG
Entry DOI10.2210/pdb5vkg/pdb
NMR InformationBMRB: 30285
DescriptorTumor susceptibility gene 101 protein, 4-methoxy-1-(5-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)-3,5-dimethyl-2-(sulfanylmethyl)pyridin-1-ium (2 entities in total)
Functional Keywordsescrt-i, inhibitor, cell cycle, cell cycle-inhibitor complex, cell cycle/inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm : Q99816
Total number of polymer chains1
Total formula weight16890.62
Authors
Strickland, M.,Ehrlich, L.S.,Watanabe, S.,Khan, M.,Strub, M.-P.,Luan, C.H.,Powell, M.D.,Leis, J.,Tjandra, N.,Carter, C. (deposition date: 2017-04-21, release date: 2017-11-15, Last modification date: 2023-06-14)
Primary citationStrickland, M.,Ehrlich, L.S.,Watanabe, S.,Khan, M.,Strub, M.P.,Luan, C.H.,Powell, M.D.,Leis, J.,Tjandra, N.,Carter, C.A.
Tsg101 chaperone function revealed by HIV-1 assembly inhibitors.
Nat Commun, 8:1391-1391, 2017
Cited by
PubMed: 29123089
DOI: 10.1038/s41467-017-01426-2
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

数据于2024-03-27公开中

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