5VFR

Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome

Summary for 5VFR

Related5VFS 5VFO 5VFP 5VFQ 5VFT 5VFU
EMDB information8665 8662 8663 8664 8666 8667 8668
Descriptor26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome non-ATPase regulatory subunit 12, ... (34 entities in total)
Functional Keywords26s proteasome, atp-dependent protease, aaa-atpase, peptide-unfolding channel, 20s core particle, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains46
Total molecular weight1522353.54
Authors
Zhu, Y.,Wang, W.L.,Yu, D.,Ouyang, Q.,Lu, Y.,Mao, Y. (deposition date: 2017-04-09, release date: 2018-07-18)
Primary citation
Zhu, Y.,Wang, W.L.,Yu, D.,Ouyang, Q.,Lu, Y.,Mao, Y.
Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9:1360-1360, 2018
PubMed: 29636472 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-03785-w
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers100.6%0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

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