5UC3

Structure of the dominant negative mutant Glucocorticoid Receptor alpha (L733K/N734P) complexed with RU-486

Summary for 5UC3

• Entry DOI: 10.2210/pdb5uc3/pdb
• Descriptor: Glucocorticoid receptor, 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total)
• Functional Keywords: nuclear receptor, hormone receptor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 61728.21

Authors

Min, J.,Cidlowski, J.A.,Pedersen, L.C. (deposition date: 2016-12-21, release date: 2017-12-27, Last modification date: 2023-10-04)

• Primary citation: Min, J.,Pedersen, L.C.; Nuclear receptor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.009 Å)