5TV4

3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc

5TV4 の概要

• エントリーDOI: 10.2210/pdb5tv4/pdb
• EMDBエントリー: 8469
• 分子名称: Lipid A export ATP-binding/permease protein MsbA, L-glycero-alpha-D-manno-heptopyranose-(1-7)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-alpha-D-glucopyranose, PHOSPHATE ION, ... (6 entities in total)
• 機能のキーワード: abc transporter, lps, flippase, nanodisc, hydrolase
• 由来する生物種: Escherichia coli O157:H7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 137764.12

構造登録者

Mi, W.,Walz, T.,Liao, M. (登録日: 2016-11-08, 公開日: 2017-09-20, 最終更新日: 2020-07-29)

• 主引用文献: Mi, W.,Li, Y.,Yoon, S.H.,Ernst, R.K.,Walz, T.,Liao, M.; Structural basis of MsbA-mediated lipopolysaccharide transport.; Nature, 549:233-237, 2017; PubMed: 28869968; DOI: 10.1038/nature23649

実験手法

ELECTRON MICROSCOPY (4.2 Å)