5TIH

Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA

Summary for 5TIH

• Entry DOI: 10.2210/pdb5tih/pdb
• Related: 5TIK
• Descriptor: Cysteine-rich protective antigen, CyRPA antibody Fab Heavy Chain, CyRPA antibody Fab Light Chain, ... (5 entities in total)
• Functional Keywords: plasmodium falciparum cyrpa inhibitory antibody, immune system
• Biological source: Plasmodium falciparum; More
• Total number of polymer chains: 3
• Total formula weight: 86538.62

Authors

Chen, L.,Xu, Y.,Wang, W.,Thompson, J.K.,Goddard-Borger, E.,Lawrence, M.C.,Cowman, A.F. (deposition date: 2016-10-03, release date: 2017-03-01, Last modification date: 2023-10-04)

• Primary citation: Chen, L.,Xu, Y.,Wong, W.,Thompson, J.K.,Healer, J.,Goddard-Borger, E.D.,Lawrence, M.C.,Cowman, A.F.; Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.; Elife, 6:-, 2017; PubMed: 28195530; DOI: 10.7554/eLife.21347

Experimental method

X-RAY DIFFRACTION (2.44 Å)