5THN

Crystal Structure of 2-Hydroxycyclohepta-2,4,6-triene-1-thione bound to human carbonic anhydrase 2

Summary for 5THN

• Entry DOI: 10.2210/pdb5thn/pdb
• Related: 5TH4 5THI 5THJ 5TI0
• Descriptor: Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ... (7 entities in total)
• Functional Keywords: carbonic anhydrase 2, complex, metalloenzyme inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 30098.58

Authors

Dick, B.,Cohen, S. (deposition date: 2016-09-29, release date: 2017-04-26, Last modification date: 2023-10-04)

• Primary citation: Dick, B.L.,Patel, A.,McCammon, J.A.,Cohen, S.M.; Effect of donor atom identity on metal-binding pharmacophore coordination.; J. Biol. Inorg. Chem., 22:605-613, 2017; PubMed: 28389830; DOI: 10.1007/s00775-017-1454-3

Experimental method

X-RAY DIFFRACTION (1.33 Å)