5T90

Structural mechanisms for alpha-conotoxin selectivity at the human alpha3beta4 nicotinic acetylcholine receptor

Summary for 5T90

• Entry DOI: 10.2210/pdb5t90/pdb
• Descriptor: Acetylcholine-binding protein, LsIA (3 entities in total)
• Functional Keywords: alpha-conotoxins, acetylcholine binding protein, nicotinic acetylcholine receptor, protein binding
• Biological source: Lymnaea stagnalis (Great pond snail); More
• Total number of polymer chains: 10
• Total formula weight: 128067.63

Authors

Abraham, N.,Healy, M.,Ragnarsson, L.,Brust, A.,Alewood, P.,Lewis, R. (deposition date: 2016-09-08, release date: 2017-04-12, Last modification date: 2023-10-04)

• Primary citation: Abraham, N.,Healy, M.,Ragnarsson, L.,Brust, A.,Alewood, P.F.,Lewis, R.J.; Structural mechanisms for alpha-conotoxin activity at the human alpha 3 beta 4 nicotinic acetylcholine receptor.; Sci Rep, 7:45466-45466, 2017; PubMed: 28361878; DOI: 10.1038/srep45466

Experimental method

X-RAY DIFFRACTION (2.8 Å)