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5SXV

X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a resting state

Summary for 5SXV
Entry DOI10.2210/pdb5sxv/pdb
Related5SXU
DescriptorCys-loop ligand-gated ion channel, 2-BROMOETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywordselic, anesthetic, ethanol, resting state, transport protein
Biological sourceDickeya chrysanthemi (Pectobacterium chrysanthemi)
Total number of polymer chains10
Total formula weight374741.25
Authors
Chen, Q.,Kinde, M.,Cohen, A.,Xu, Y.,Tang, P. (deposition date: 2016-08-10, release date: 2017-06-21, Last modification date: 2023-10-04)
Primary citationChen, Q.,Wells, M.M.,Tillman, T.S.,Kinde, M.N.,Cohen, A.,Xu, Y.,Tang, P.
Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.
Structure, 25:180-187, 2017
Cited by
PubMed: 27916519
DOI: 10.1016/j.str.2016.11.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.4 Å)
Structure validation

217705

數據於2024-03-27公開中

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