5OYJ

Crystal structure of VEGFR-2 domains 4-5 in complex with DARPin D4b

Summary for 5OYJ

Entry DOI	10.2210/pdb5oyj/pdb
Related PRD ID	PRD_900006
Descriptor	DARPin D4b, Vascular endothelial growth factor receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	glycoprotein receptor kinase designed ankyrin repeat protein angiogenesis, signaling protein
Biological source	synthetic construct More
Total number of polymer chains	4
Total formula weight	93563.33
Authors	Piscitelli, C.L.,Thieltges, K.M.,Markovic-Mueller, S.,Binz, H.K.,Ballmer-Hofer, K. (deposition date: 2017-09-10, release date: 2018-03-14, Last modification date: 2024-01-17)
Primary citation	Thieltges, K.M.,Avramovic, D.,Piscitelli, C.L.,Markovic-Mueller, S.,Binz, H.K.,Ballmer-Hofer, K. Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling. Angiogenesis, 21:533-543, 2018 Cited by PubMed: 29502220 DOI: 10.1007/s10456-018-9606-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.38 Å)

Structure validation