5OQ0

Crystal structure of transthyretin mutant 87-110-117

Summary for 5OQ0

• Entry DOI: 10.2210/pdb5oq0/pdb
• Descriptor: Transthyretin (2 entities in total)
• Functional Keywords: amyloidosis, homo-tetramer, retinol-binding protein, ttr, transport protein
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted: P02766
• Total number of polymer chains: 1
• Total formula weight: 13821.46

Authors

Zanotti, G.,Vallese, F.,Berni, R. (deposition date: 2017-08-10, release date: 2017-12-27, Last modification date: 2024-01-17)

• Primary citation: Zanotti, G.,Vallese, F.,Ferrari, A.,Menozzi, I.,Saldano, T.E.,Berto, P.,Fernandez-Alberti, S.,Berni, R.; Structural and dynamics evidence for scaffold asymmetric flexibility of the human transthyretin tetramer.; PLoS ONE, 12:e0187716-e0187716, 2017; PubMed: 29240759; DOI: 10.1371/journal.pone.0187716

Experimental method

X-RAY DIFFRACTION (1.94 Å)