5OI7

Human CEP85 - coiled coil domain 4

Summary for 5OI7

Entry DOI	10.2210/pdb5oi7/pdb
Descriptor	Centrosomal protein of 85 kDa, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywords	centrosomes, centriole, cep85, stil, protein binding
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : Q6P2H3
Total number of polymer chains	2
Total formula weight	20813.04
Authors	van Breugel, M. (deposition date: 2017-07-18, release date: 2018-04-18, Last modification date: 2024-01-17)
Primary citation	Liu, Y.,Gupta, G.D.,Barnabas, D.D.,Agircan, F.G.,Mehmood, S.,Wu, D.,Coyaud, E.,Johnson, C.M.,McLaughlin, S.H.,Andreeva, A.,Freund, S.M.V.,Robinson, C.V.,Cheung, S.W.T.,Raught, B.,Pelletier, L.,van Breugel, M. Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly. Nat Commun, 9:1731-1731, 2018 Cited by PubMed: 29712910 DOI: 10.1038/s41467-018-04122-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation