5OEY

Crystal structure of Leishmania major fructose-1,6-bisphosphatase in holo form.

Summary for 5OEY

Entry DOI	10.2210/pdb5oey/pdb
Descriptor	FBP protein, PHOSPHATE ION, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywords	allostery, gluconeogenesis, hydrolase
Biological source	Leishmania major
Total number of polymer chains	4
Total formula weight	156849.56
Authors	Yuan, M.,Vasquez-Valdivieso, M.G.,McNae, I.W.,Michels, P.A.M.,Fothergill-Gilmore, L.A.,Walkinshaw, M.D. (deposition date: 2017-07-10, release date: 2017-09-20, Last modification date: 2024-01-17)
Primary citation	Yuan, M.,Vasquez-Valdivieso, M.G.,McNae, I.W.,Michels, P.A.M.,Fothergill-Gilmore, L.A.,Walkinshaw, M.D. Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition. J. Mol. Biol., 429:3075-3089, 2017 Cited by PubMed: 28882541 DOI: 10.1016/j.jmb.2017.08.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation