5OD1

Structure of the engineered metalloesterase MID1sc10 complexed with a phosphonate transition state analogue

Summary for 5OD1

Entry DOI	10.2210/pdb5od1/pdb
Descriptor	MID1sc10, ZINC ION, [2-oxidanylidene-7-[oxidanyl-[(1~{S})-1-phenylethyl]phosphoryl]oxy-chromen-4-yl]methanesulfonic acid, ... (5 entities in total)
Functional Keywords	directed evolution, engineered metalloenzyme, de novo protein-hydrolase, de novo protein-hydrolase complex, de novo protein/hydrolase
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	11450.94
Authors	Mittl, P.R.E.,Studer, S.,Hansen, D.A.,Hilvert, D. (deposition date: 2017-07-04, release date: 2018-12-12, Last modification date: 2020-04-22)
Primary citation	Studer, S.,Hansen, D.A.,Pianowski, Z.L.,Mittl, P.R.E.,Debon, A.,Guffy, S.L.,Der, B.S.,Kuhlman, B.,Hilvert, D. Evolution of a highly active and enantiospecific metalloenzyme from short peptides. Science, 362:1285-1288, 2018 Cited by PubMed: 30545884 DOI: 10.1126/science.aau3744 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.34 Å)

Structure validation