5O57

Solution Structure of the N-terminal Region of Dkk4

Summary for 5O57

• Entry DOI: 10.2210/pdb5o57/pdb
• NMR Information: BMRB: 34146
• Descriptor: Dickkopf-related protein 4 (1 entity in total)
• Functional Keywords: dkk4, wnt signalling, cysteine-rich domain 1, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 10931.42

Authors

Waters, L.C.,Patel, S.,Barkell, A.M.,Muskett, F.W.,Robinson, M.K.,Holdsworth, G.,Carr, M.D. (deposition date: 2017-06-01, release date: 2018-06-13, Last modification date: 2023-06-14)

• Primary citation: Patel, S.,Barkell, A.M.,Gupta, D.,Strong, S.L.,Bruton, S.,Muskett, F.W.,Addis, P.W.,Renshaw, P.S.,Slocombe, P.M.,Doyle, C.,Clargo, A.,Taylor, R.J.,Prosser, C.E.,Henry, A.J.,Robinson, M.K.,Waters, L.C.,Holdsworth, G.,Carr, M.D.; Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.; J. Biol. Chem., 293:12149-12166, 2018; PubMed: 29925589; DOI: 10.1074/jbc.RA118.002918

Experimental method

SOLUTION NMR