5NFW

Neutron structure of human transthyretin (TTR) S52P mutant at room temperature to 1.8A resolution (quasi-Laue)

Summary for 5NFW

• Entry DOI: 10.2210/pdb5nfw/pdb
• Related: 5NFE
• Descriptor: Transthyretin (2 entities in total)
• Functional Keywords: transthyretin, prealbumin, homotetramer, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 28093.45

Authors

Yee, A.W.,Moulin, M.,Blakeley, M.P.,Cooper, J.B.,Haertlein, M.,Mitchell, E.P.,Forsyth, V.T. (deposition date: 2017-03-16, release date: 2019-01-02, Last modification date: 2019-03-20)

• Primary citation: Yee, A.W.,Aldeghi, M.,Blakeley, M.P.,Ostermann, A.,Mas, P.J.,Moulin, M.,de Sanctis, D.,Bowler, M.W.,Mueller-Dieckmann, C.,Mitchell, E.P.,Haertlein, M.,de Groot, B.L.,Boeri Erba, E.,Forsyth, V.T.; A molecular mechanism for transthyretin amyloidogenesis.; Nat Commun, 10:925-925, 2019; PubMed: 30804345; DOI: 10.1038/s41467-019-08609-z

Experimental method

NEUTRON DIFFRACTION (1.8 Å)
X-RAY DIFFRACTION (1.8 Å)