5NF7

Structure of Galectin-3 CRD in complex with compound 1

Summary for 5NF7

• Entry DOI: 10.2210/pdb5nf7/pdb
• Descriptor: Galectin-3, beta-D-galactopyranose-(1-4)-N-acetyl-2-(acetylamino)-2-deoxy-beta-D-glucopyranosylamine (3 entities in total)
• Functional Keywords: galectin-3 crd, cation-pi interactions, sugar binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 20359.83

Authors

Ronin, C.,Atmanene, C.,Gautier, F.M.,Pilard, F.D.,Teletchea, S.,Ciesielski, F.,Hannah, V.V.,Grandjean, C. (deposition date: 2017-03-13, release date: 2017-06-21, Last modification date: 2024-01-17)

• Primary citation: Atmanene, C.,Ronin, C.,Teletchea, S.,Gautier, F.M.,Djedaini-Pilard, F.,Ciesielski, F.,Vivat, V.,Grandjean, C.; Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3.; Biochem. Biophys. Res. Commun., 489:281-286, 2017; PubMed: 28554839; DOI: 10.1016/j.bbrc.2017.05.150

Experimental method

X-RAY DIFFRACTION (1.59 Å)