5NBU
Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations
Summary for 5NBU
Entry DOI | 10.2210/pdb5nbu/pdb |
Descriptor | Alpha-1-antitrypsin, GLYCEROL, OXAMIC ACID, ... (4 entities in total) |
Functional Keywords | serpin, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 42702.60 |
Authors | Huntington, J.A.,Pomowski, A.,Johnson, D.J.D. (deposition date: 2017-03-02, release date: 2018-03-21, Last modification date: 2024-01-17) |
Primary citation | Johnson, D.J.D.,Pomowski, A.,Huntington, J.A. CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
Download full validation report