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5MZO

UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (open conformation)

Summary for 5MZO
Entry DOI10.2210/pdb5mzo/pdb
DescriptorUDP-glucose-glycoprotein glucosyltransferase-like protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordsglycoprotein, misfolding, transferase, endoplasmic reticulum
Biological sourceChaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Total number of polymer chains1
Total formula weight172207.78
Authors
Roversi, P.,Caputo, A.T.,Hill, J.,Alonzi, D.S.,Zitzmann, N. (deposition date: 2017-02-01, release date: 2017-07-26, Last modification date: 2024-01-17)
Primary citationRoversi, P.,Marti, L.,Caputo, A.T.,Alonzi, D.S.,Hill, J.C.,Dent, K.C.,Kumar, A.,Levasseur, M.D.,Lia, A.,Waksman, T.,Basu, S.,Soto Albrecht, Y.,Qian, K.,McIvor, J.P.,Lipp, C.B.,Siliqi, D.,Vasiljevic, S.,Mohammed, S.,Lukacik, P.,Walsh, M.A.,Santino, A.,Zitzmann, N.
Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.
Proc. Natl. Acad. Sci. U.S.A., 114:8544-8549, 2017
Cited by
PubMed: 28739903
DOI: 10.1073/pnas.1703682114
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.48 Å)
Structure validation

217705

數據於2024-03-27公開中

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