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5ME8

N-terminal domain of the human tumor suppressor ING5

Summary for 5ME8
Entry DOI10.2210/pdb5me8/pdb
DescriptorInhibitor of growth protein 5, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordstumor suppressor, ing5, asymmetric dimer, transcription
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight25795.36
Authors
Roversi, P.,Blanco, F.J.,Rojas, A.L.,Buitrago, J.A.R. (deposition date: 2016-11-14, release date: 2018-03-14, Last modification date: 2024-01-17)
Primary citationOrmaza, G.,Rodriguez, J.A.,Ibanez de Opakua, A.,Merino, N.,Villate, M.,Gorrono, I.,Rabano, M.,Palmero, I.,Vilaseca, M.,Kypta, R.,Vivanco, M.D.M.,Rojas, A.L.,Blanco, F.J.
The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431:2298-2319, 2019
Cited by
PubMed: 31026448
DOI: 10.1016/j.jmb.2019.04.018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

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