5ME8
N-terminal domain of the human tumor suppressor ING5
Summary for 5ME8
Entry DOI | 10.2210/pdb5me8/pdb |
Descriptor | Inhibitor of growth protein 5, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | tumor suppressor, ing5, asymmetric dimer, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 25795.36 |
Authors | Roversi, P.,Blanco, F.J.,Rojas, A.L.,Buitrago, J.A.R. (deposition date: 2016-11-14, release date: 2018-03-14, Last modification date: 2024-01-17) |
Primary citation | Ormaza, G.,Rodriguez, J.A.,Ibanez de Opakua, A.,Merino, N.,Villate, M.,Gorrono, I.,Rabano, M.,Palmero, I.,Vilaseca, M.,Kypta, R.,Vivanco, M.D.M.,Rojas, A.L.,Blanco, F.J. The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark. J.Mol.Biol., 431:2298-2319, 2019 Cited by PubMed: 31026448DOI: 10.1016/j.jmb.2019.04.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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