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6RUR

Structure of the SCIN stabilized C3bBb convertase bound to properdin

Replaces:  5M6W
Summary for 6RUR
Entry DOI10.2210/pdb6rur/pdb
DescriptorProperdin, alpha-D-mannopyranose, MAGNESIUM ION, ... (11 entities in total)
Functional Keywordsinnate immunity, complement, protease, immune system
Biological sourceHomo sapiens (Human)
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Total number of polymer chains12
Total formula weight592636.33
Authors
Pedersen, D.V.,Gadeberg, T.A.F.,Andersen, G.R. (deposition date: 2019-05-29, release date: 2019-08-21, Last modification date: 2024-01-24)
Primary citationPedersen, D.V.,Gadeberg, T.A.F.,Thomas, C.,Wang, Y.,Joram, N.,Jensen, R.K.,Mazarakis, S.M.M.,Revel, M.,El Sissy, C.,Petersen, S.V.,Lindorff-Larsen, K.,Thiel, S.,Laursen, N.S.,Fremeaux-Bacchi, V.,Andersen, G.R.
Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Front Immunol, 10:2007-2007, 2019
Cited by
PubMed: 31507604
DOI: 10.3389/fimmu.2019.02007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (6 Å)
Structure validation

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