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5LWE

Crystal structure of the human CC chemokine receptor type 9 (CCR9) in complex with vercirnon

Summary for 5LWE
Entry DOI10.2210/pdb5lwe/pdb
DescriptorC-C chemokine receptor type 9, Vercirnon, OLEIC ACID, ... (6 entities in total)
Functional Keywordsmembrane protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight85145.27
Authors
Oswald, C.,Rappas, M.,Kean, J.,Dore, A.S.,Errey, J.C.,Bennett, K.,Deflorian, F.,Christopher, J.A.,Jazayeri, A.,Mason, J.S.,Congreve, M.,Cooke, R.M.,Marshall, F.H. (deposition date: 2016-09-16, release date: 2016-12-07, Last modification date: 2024-01-17)
Primary citationOswald, C.,Rappas, M.,Kean, J.,Dore, A.S.,Errey, J.C.,Bennett, K.,Deflorian, F.,Christopher, J.A.,Jazayeri, A.,Mason, J.S.,Congreve, M.,Cooke, R.M.,Marshall, F.H.
Intracellular allosteric antagonism of the CCR9 receptor.
Nature, 540:462-465, 2016
Cited by
PubMed: 27926729
DOI: 10.1038/nature20606
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

數據於2024-03-27公開中

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