5LC8

Crystal Structure of specific mutant from Pseudomonas aeruginosa Lipoxygenase at 1.8A resolution

Summary for 5LC8

Entry DOI	10.2210/pdb5lc8/pdb
Descriptor	Arachidonate 15-lipoxygenase, FE (II) ION, GLYCEROL, ... (7 entities in total)
Functional Keywords	non-heme iron enzyme, protein-phospholipid complex, oxidoreductase, a420g mutant, eicosanoids, infectious diseases, arachidonate 15s-lipoxygenase, linoleate 13s-lipoxygenase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	73809.29
Authors	Kalms, J.,Banthiya, S.,Galemou Yoga, E.,Kuhn, H.,Scheerer, P. (deposition date: 2016-06-20, release date: 2017-01-25, Last modification date: 2024-01-10)
Primary citation	Kalms, J.,Banthiya, S.,Galemou Yoga, E.,Hamberg, M.,Holzhutter, H.G.,Kuhn, H.,Scheerer, P. The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Biochim. Biophys. Acta, 1862:463-473, 2017 Cited by PubMed: 28093240 DOI: 10.1016/j.bbalip.2017.01.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation