5KNN

Evolutionary gain of alanine mischarging to non-cognate tRNAs with a G4:U69 base pair

Summary for 5KNN

• Entry DOI: 10.2210/pdb5knn/pdb
• Descriptor: Alanine--tRNA ligase, cytoplasmic, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE (2 entities in total)
• Functional Keywords: trna synthetase, ligase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : P49588
• Total number of polymer chains: 8
• Total formula weight: 408325.18

Authors

Sun, L.,He, W.,Yang, X.-L. (deposition date: 2016-06-28, release date: 2016-09-28, Last modification date: 2023-09-27)

• Primary citation: Sun, L.,Gomes, A.C.,He, W.,Zhou, H.,Wang, X.,Pan, D.W.,Schimmel, P.,Pan, T.,Yang, X.L.; Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.; J.Am.Chem.Soc., 138:12948-12955, 2016; PubMed: 27622773; DOI: 10.1021/jacs.6b07121

Experimental method

X-RAY DIFFRACTION (2.68 Å)