5KLK
Crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase N169D in complex with NAD+ and 2-hydroxymuconate-6-semialdehyde
Summary for 5KLK
Entry DOI | 10.2210/pdb5klk/pdb |
Related | 5KLL 5KLM 5KLN 5KLO |
Descriptor | 2-aminomuconate 6-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (2E,4E)-2-hydroxy-6-oxohexa-2,4-dienoic acid, ... (5 entities in total) |
Functional Keywords | 2-aminomuconate 6-semialdehyde dehydrogenase, kynurenine pathway, oxidoreductase |
Biological source | Pseudomonas fluorescens |
Total number of polymer chains | 4 |
Total formula weight | 227741.11 |
Authors | |
Primary citation | Yang, Y.,Davis, I.,Ha, U.,Wang, Y.,Shin, I.,Liu, A. A Pitcher-and-Catcher Mechanism Drives Endogenous Substrate Isomerization by a Dehydrogenase in Kynurenine Metabolism. J.Biol.Chem., 291:26252-26261, 2016 Cited by PubMed: 27810899DOI: 10.1074/jbc.M116.759712 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.006 Å) |
Structure validation
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