5KCS

Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Evernimycin, mRNA, TetM and P-site tRNA at 3.9A resolution

This is a non-PDB format compatible entry.

Summary for 5KCS

• Entry DOI: 10.2210/pdb5kcs/pdb
• Related: 5KCR
• EMDB information: 8237 8238
• Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... (59 entities in total)
• Functional Keywords: avilamycin, evernimycin, antibiotic, antimicrobial, ribosome, cryo-em, smfret, rrna, l16, resistance, translation
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 58
• Total formula weight: 2302639.41

Authors

Arenz, S.,Juette, M.F.,Graf, M.,Nguyen, F.,Huter, P.,Polikanov, Y.S.,Blanchard, S.C.,Wilson, D.N. (deposition date: 2016-06-06, release date: 2016-08-17, Last modification date: 2019-12-25)

• Primary citation: Arenz, S.,Juette, M.F.,Graf, M.,Nguyen, F.,Huter, P.,Polikanov, Y.S.,Blanchard, S.C.,Wilson, D.N.; Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.; Proc.Natl.Acad.Sci.USA, 113:7527-7532, 2016; PubMed: 27330110; DOI: 10.1073/pnas.1604790113

Experimental method

ELECTRON MICROSCOPY (3.9 Å)