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5K9O

Crystal structure of multidonor HV1-18+HD3-9 class broadly neutralizing Influenza A antibody 31.b.09 in complex with Hemagglutinin H1 A/California/04/2009

Summary for 5K9O
Entry DOI10.2210/pdb5k9o/pdb
Descriptor31.b.09 Heavy Fv, 31.b.09 Light Fv, Hemagglutinin, ... (4 entities in total)
Functional Keywordshv1-18, multidonor, h5, universal influenza vaccine, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains6
Total formula weight210813.38
Authors
Joyce, M.G.,Thomas, P.V.,Wheatley, A.K.,McDermott, A.B.,Mascola, J.R.,Kwong, P.D. (deposition date: 2016-06-01, release date: 2016-12-28, Last modification date: 2023-09-27)
Primary citationJoyce, M.G.,Wheatley, A.K.,Thomas, P.V.,Chuang, G.Y.,Soto, C.,Bailer, R.T.,Druz, A.,Georgiev, I.S.,Gillespie, R.A.,Kanekiyo, M.,Kong, W.P.,Leung, K.,Narpala, S.N.,Prabhakaran, M.S.,Yang, E.S.,Zhang, B.,Zhang, Y.,Asokan, M.,Boyington, J.C.,Bylund, T.,Darko, S.,Lees, C.R.,Ransier, A.,Shen, C.H.,Wang, L.,Whittle, J.R.,Wu, X.,Yassine, H.M.,Santos, C.,Matsuoka, Y.,Tsybovsky, Y.,Baxa, U.,Mullikin, J.C.,Subbarao, K.,Douek, D.C.,Graham, B.S.,Koup, R.A.,Ledgerwood, J.E.,Roederer, M.,Shapiro, L.,Kwong, P.D.,Mascola, J.R.,McDermott, A.B.
Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166:609-623, 2016
Cited by
PubMed: 27453470
DOI: 10.1016/j.cell.2016.06.043
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.387 Å)
Structure validation

217705

數據於2024-03-27公開中

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