5JWD

Crystal structure of H-2Db in complex with the LCMV-derived GP392-401 peptide

Summary for 5JWD

• Entry DOI: 10.2210/pdb5jwd/pdb
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Pre-glycoprotein polyprotein GP complex, ... (6 entities in total)
• Functional Keywords: immunology, antigen presentation, mhc class i, immune system
• Biological source: Mus musculus (Mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887; Stable signal peptide: Virion membrane ; Multi-pass membrane protein . Glycoprotein G1: Virion membrane ; Peripheral membrane protein . Glycoprotein G2: Virion membrane ; Single-pass membrane protein : P09991
• Total number of polymer chains: 3
• Total formula weight: 44990.36

Authors

Buratto, J.,Badia-Martinez, D.,Norstrom, M.,Sandalova, T.,Achour, A. (deposition date: 2016-05-12, release date: 2017-05-24, Last modification date: 2024-01-10)

• Primary citation: Hafstrand, I.,Badia-Martinez, D.,Josey, B.J.,Norstrom, M.,Buratto, J.,Pellegrino, S.,Duru, A.D.,Sandalova, T.,Achour, A.; Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.; PLoS ONE, 12:e0189584-e0189584, 2017; PubMed: 29253009; DOI: 10.1371/journal.pone.0189584

Experimental method

X-RAY DIFFRACTION (2.5 Å)