5JWA

the structure of malaria PfNDH2

Summary for 5JWA

Entry DOI	10.2210/pdb5jwa/pdb
Related	5JWA 5JWC
Descriptor	NADH dehydrogenase, putative, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	pfndh2, fad, membrane protein-inhibitor complex, membrane protein/inhibitor
Biological source	Plasmodium falciparum (isolate 3D7)
Total number of polymer chains	2
Total formula weight	125187.55
Authors	Yu, Y.,Yang, Y.Q.,Li, X.L.,Yu, J.,Ge, J.P.,Li, J.,Rao, Y.,Yang, M.J. (deposition date: 2016-05-11, release date: 2017-03-22, Last modification date: 2023-11-08)
Primary citation	Yang, Y.,Yu, Y.,Li, X.,Li, J.,Wu, Y.,Yu, J.,Ge, J.,Huang, Z.,Jiang, L.,Rao, Y.,Yang, M. Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria J. Med. Chem., 60:1994-2005, 2017 Cited by PubMed: 28195463 DOI: 10.1021/acs.jmedchem.6b01733 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.162 Å)

Structure validation